Although islet transplantation is an option for patients with type 1 diabetes, even those who become insulin-independent after engraftment have islet-graft function that is estimated to be less than ...

The endocrine pancreas is composed of clusters of cells, or islets, which secrete endocrine factors important for systemic metabolism, including insulin and glucagon. A large proportion of the islet ...

Phenotyping and genotyping initiatives within the Integrated Islet Distribution Program (IIDP), the largest source of human islets for research in the U.S., provide standardized assessment of islet ...

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine ...