A paper published in Nature Communications shows that when neurons are given information about the changing world around them (task-related sensory input) it changes how they behave, putting them on ...
Loss- and gain-of-function variants in the gene encoding KCNQ2 channels are a common cause of developmental and epileptic encephalopathy, a condition characterized by seizures, developmental delays, ...
Excitation/inhibition balance is crucial to homeostatic brain function and disrupted in several neurodevelopmental and neurodegenerative diseases. Cortical inhibitory neurons derived from the medial ...
Researchers have used microRNA-based direct reprogramming to generate neurons from fibroblasts, providing new insights into late-onset Alzheimer’s disease. Aging is the most significant risk factor ...
An EEG (electroencephalogram) is a painless test that uses small sensors placed on the scalp to measure the brain’s electrical activity. It provides a real-time readout of brain “waves”—rhythms ...
The spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer’s disease and frontotemporal dementia—has been studied with a model that incorporates human ...
The new model developed by Flatiron Institute researchers proposes that biological neurons have more control over their surroundings than previously thought, something that could be replicated in the ...
Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...
In a recent study published in the journal Nature Neuroscience, researchers investigated the contributions of oligodendrocytes (OLs) and neurons to amyloid-β (Aβ) plaque burden in Alzheimer's disease ...