A multi-institutional team of researchers led by Case Western Reserve University has identified a pattern of clustered genetic changes that appear to encourage growth of colorectal cancer tumors—a ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

In a time when what defines gender is being questioned and discussed, a new study reveals that single changes in DNA make ...

Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

One extra letter of DNA. That was all it took to override an entire chromosome’s worth of instructions and turn a female ...

Scientists discovered that making a very small change to female mice's DNA caused them to develop male reproductive organs.