Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

In conclusion, we have demonstrated the application of the natural protein clathrin and its subunits to assemble large and regular surface-bound lattices. The essential aspect of durability is ...

After it fills with cargo, the pit pinches off to form a clathrin-coated, membrane-bound vesicle inside the cell, which then proceeds to its proper destination. In cultured cells, hundreds of these ...

Asynaptic levels of the protein clathrin are a determinant factor for synaptic plasticity of neurons, researchers have shown. Neurons transmit information in a specialized contact points called ...

This study is reported by Hualan Chen’s group from the State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences.

The paper S. Kaur et al., “An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis,” eLife, 3:e00829, 2014. For decades, scientists observed clathrin-mediated ...

This is a preview. Log in through your library . Abstract The clathrin-coated pit lattice is held onto the plasma membrane by an integral membrane protein that binds the clathrin AP-2 subunit with ...

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

Endocytosis is the process by which cells take in molecules from their surroundings. Clathrin-dependent endocytosis requires the recruitment of clathrin to help curve the plasma membrane into the ...

Cells have a clever way called clathrin-mediated endocytosis to transport cargos like growth factors across the cell membrane and into the cell. Researchers used a sophisticated fluorescence ...

Researchers of the group of cellular and molecular neurobiology of the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona, led by researcher Artur Llobet, have shown ...